Articoli scientifici:
Rhoa Kinase Inhibition With Fasudil Versus Simvastatin in Murine Models of Cerebral Cavernous Malformations.
https://www.ncbi.nlm.nih.gov/pubmed/27879448
Cerebral Cavernous Malformations: Review of the Genetic and Protein–Protein Interactions Resulting in Disease Pathogenesis
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5107910/
Cerebral Cavernous Malformation, Familial
https://www.ncbi.nlm.nih.gov/books/NBK1293/
Endothelial exocytosis of angiopoietin-2 resulting from CCM3 deficiency contributes to cerebral cavernous malformation
http://www.nature.com/nm/journal/v22/n9/full/nm.4169.html
Cerebral cavernous malformations arise from endothelial gain of MEKK3–KLF2/4 signalling
http://www.nature.com/nature/journal/v532/n7597/full/nature17178.html
CCM-3/STRIPAK promotes seamless tube extension through endocytic recycling
http://www.nature.com/articles/ncomms7449
The cerebral cavernous malformation 3 gene is necessary for senescence induction.
https://www.ncbi.nlm.nih.gov/pubmed/25655101
CCM proteins control endothelial β1 integrin dependent response to shear stress
http://bio.biologists.org/content/3/12/1228.long
Strategy for identifying repurposed drugs for the treatment of cerebral cavernous malformation.
https://www.ncbi.nlm.nih.gov/pubmed/25486933
Lack of CCM1 induces hypersprouting and impairs response to flow.
https://www.ncbi.nlm.nih.gov/pubmed/24990152
Lesions from patients with sporadic cerebral cavernous malformations harbor somatic mutations in the CCM genes: evidence for a common biochemical pathway for CCM pathogenesis
https://academic.oup.com/hmg/article/23/16/4357/627919/Lesions-from-patients-with-sporadic-cerebral
Long-term natural history of incidentally discovered cavernous malformations in a single-center cohort
http://thejns.org/doi/abs/10.3171/2014.1.JNS131619?url_ver=Z39.88-2003&rfr_id=ori%3Arid%3Acrossref.org&rfr_dat=cr_pub%3Dpubmed&
Clinical course of untreated pediatric brainstem cavernous malformations: hemorrhage risk and functional recovery
http://thejns.org/doi/abs/10.3171/2014.2.PEDS13487?url_ver=Z39.88-2003&rfr_id=ori%3Arid%3Acrossref.org&rfr_dat=cr_pub%3Dpubmed
Association of Cardiovascular Risk Factors with Disease Severity in Cerebral Cavernous Malformation Type 1 Subjects with the Common Hispanic Mutation
http://www.karger.com/Article/FullText/356839
Dynamic permeability and quantitative susceptibility: related imaging biomarkers in cerebral cavernous malformations.
https://www.ncbi.nlm.nih.gov/pubmed/24302484
Long-term seizure outcomes following resection of supratentorial cavernous malformations.
https://www.ncbi.nlm.nih.gov/pubmed/24075713
Research in the News: Study uncovers potential to alleviate tissue damage during strokes or transplant
http://news.yale.edu/2013/10/28/research-news-study-uncovers-potential-alleviate-tissue-damage-during-strokes-or-transpla
Sulindac metabolites 2015
